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Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging 期刊论文
CELL, 2024, 卷号: 187, 期号: 24
作者:  Ma, Shuai;  Ji, Zhejun;  Zhang, Bin;  Geng, Lingling;  Cai, Yusheng;  Nie, Chao;  Li, Jiaming;  Zuo, Yuesheng;  Sun, Yuzhe;  Xu, Gang;  Liu, Beibei;  Ai, Jiaqi;  Liu, Feifei;  Zhao, Liyun;  Zhang, Jiachen;  Zhang, Hui;  Sun, Shuhui;  Huang, Haoyan;  Zhang, Yiyuan;  Ye, Yanxia;  Fan, Yanling;  Zheng, Fangshuo;  Hu, Jinghao;  Zhang, Baohu;  Li, Jingyi;  Feng, Xin;  Zhang, Feng;  Zhuang, Yuan;  Li, Tianjie;  Yu, Yang;  Bao, Zhaoshi;  Pan, Sipei;  Esteban, Concepcion Rodriguez;  Liu, Zhili;  Deng, Haohao;  Wen, Feng;  Song, Moshi;  Wang, Si;  Zhu, Guodong;  Yang, Jiayin;  Jiang, Tao;  Song, Weihong;  Belmonte, Juan Carlos Izpisua;  Qu, Jing;  Zhang, Weiqi;  Gu, Ying;  Li, Guang-Hui
浏览  |  Adobe PDF(42374Kb)  |  收藏  |  浏览/下载：11/1  |  提交时间：2025/11/06
CELLULAR SENESCENCE  SECRETORY PHENOTYPE  CELLS  REPROGRAMS  ATLAS  HISAT  
Metformin decelerates aging clock in male monkeys 期刊论文
CELL, 2024, 卷号: 187, 期号: 22
作者:  Yang, Yuanhan;  Lu, Xiaoyong;  Liu, Ning;  Ma, Shuai;  Zhang, Hui;  Zhang, Zhiyi;  Yang, Kuan;  Jiang, Mengmeng;  Zheng, Zikai;  Qiao, Yicheng;  Hu, Qinchao;  Huang, Ying;  Zhang, Yiyuan;  Xiong, Muzhao;  Liu, Lixiao;  Jiang, Xiaoyu;  Reddy, Pradeep;  Dong, Xueda;  Xu, Fanshu;  Wang, Qiaoran;  Zhao, Qian;  Lei, Jinghui;  Sun, Shuhui;  Jing, Ying;  Li, Jingyi;  Cai, Yusheng;  Fan, Yanling;  Yan, Kaowen;  Jing, Yaobin;  Haghani, Amin;  Xing, Mengen;  Zhang, Xuan;  Zhu, Guodong;  Song, Weihong;  Horvath, Steve;  Esteban, Concepcion Rodriguez;  Song, Moshi;  Wang, Si;  Zhao, Guoguang;  Li, Wei;  Belmonte, Juan Carlos Izpisua;  Qu, Jing;  Zhang, Weiqi;  Liu, Guang-Hui
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HUMAN PLASMA PROTEOME  SOFTWARE  PATHWAY  MORTALITY  PACKAGE  MODELS  IMAGE  
CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver 期刊论文
NUCLEIC ACIDS RESEARCH, 2024, 页码: 352-352
作者:  Li, Hong-Yu;  Wang, Min;  Jiang, Xiaoyu;  Jing, Yaobin;  Wu, Zeming;  He, Yifang;  Yan, Kaowen;  Sun, Shuhui;  Ma, Shuai;  Ji, Zhejun;  Wang, Si;  Belmonte, Juan Carlos Izpisua;  Qu, Jing;  Zhang, Weiqi;  Wei, Taotao;  Liu, Guang-Hui
浏览  |  Adobe PDF(2773Kb)  |  收藏  |  浏览/下载：10/0  |  提交时间：2025/11/06
LIFE-SPAN EXTENSION  RIBOSOME BIOGENESIS  STEM-CELLS  RNA  CANCER  TRANSCRIPTION  HOMEOSTASIS  ACTIVATION  KNOCKOUT  SUBUNITS  
The sirtuin-associated human senescence program converges on the activation of PAPPA 期刊论文
DEVELOPMENTAL CELL, 2024, 卷号: 59, 期号: 8, 页码: 364-384
作者:  Bi, Shijia;  Jiang, Xiaoyu;  Ji, Qianzhao;  Wang, Zehua;  Ren, Jie;  Wang, Si;  Yu, Yang;  Wang, Ruoqi;  Liu, Zunpeng;  Liu, Junhang;  Hu, Jianli;  Sun, Guoqiang;  Wu, Zeming;  Diao, Zhiqing;  Li, Jingyi;  Sun, Liang;  Belmonte, Juan Carlos Izpisua;  Zhang, Weiqi;  Liu, Guang-Hui;  Qu, Jing
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PLASMA-PROTEIN-A  TRANSCRIPTIONAL ACTIVATION  READ ALIGNMENT  DOMAINS  ORGANIZATION  EXPRESSION  REGULATOR  STRESS  CTCF  HETEROCHROMATIN  
Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice 期刊论文
CELL REPORTS MEDICINE, 2024, 卷号: 5, 期号: 3
作者:  Hernandez-Benitez, Reyna;  Wang, Chao;  Shi, Lei;  Ouchi, Yasuo;  Zhong, Cuiqing;  Hishida, Tomoaki;  Liao, Hsin-Kai;  Magill, Eric A.;  Memczak, Sebastian;  Soligalla, Rupa D.;  Fresia, Chiara;  Hatanaka, Fumiyuki;  Lamas, Veronica;  Guillen, Isabel;  Sahu, Sanjeeb;  Yamamoto, Mako;  Shao, Yanjiao;  Aguirre-Vazquez, Alain;  Delicado, Estrella Nunez;  Guillen, Pedro;  Esteban, Concepcion Rodriguez;  Qu, Jing;  Reddy, Pradeep;  Horvath, Steve;  Liu, Guang-Hui;  Magistretti, Pierre;  Belmonte, Juan Carlos Izpisua
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ENRICHMENT ANALYSIS  WEB SERVER  STEM-CELLS  DIFFERENTIATION  PLURIPOTENCY  EXPRESSION  PROLIFERATION  
Aging induces region-specific dysregulation of hormone synthesis in the primate adrenal gland 期刊论文
NATURE AGING, 2024, 卷号: 4, 期号: 3
作者:  Wang, Qiaoran;  Wang, Xuebao;  Liu, Beibei;  Ma, Shuai;  Zhang, Feng;  Sun, Shuhui;  Jing, Yaobin;  Fan, Yanling;  Ding, Yingjie;  Xiong, Muzhao;  Li, Jiaming;  Zhai, Qiaocheng;  Zheng, Yandong;  Liu, Chengyu;  Xu, Gang;  Yang, Jiayin;  Wang, Si;  Ye, Jinlin;  Belmonte, Juan Carlos Izpisua;  Qu, Jing;  Liu, Guang-Hui;  Zhang, Weiqi
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DEHYDROEPIANDROSTERONE-SULFATE  GENE-EXPRESSION  STEROIDOGENESIS  BIOMARKER  ZONATION  HUMANS  FAMILY  
A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes 期刊论文
PROTEIN & CELL, 2024, 卷号: 15, 期号: 2, 页码: 98-120
作者:  Yang, Shanshan;  Liu, Chengyu;  Jiang, Mengmeng;  Liu, Xiaoqian;  Geng, Lingling;  Zhang, Yiyuan;  Sun, Shuhui;  Wang, Kang;  Yin, Jian;  Ma, Shuai;  Wang, Si;  Belmonte, Juan Carlos Izpisua;  Zhang, Weiqi;  Qu, Jing;  Liu, Guang-Hui
浏览  |  Adobe PDF(31403Kb)  |  收藏  |  浏览/下载：8/1  |  提交时间：2025/11/06
AGE-RELATED-CHANGES  SPECIES-DIFFERENCES  STELLATE CELLS  TGF-BETA  CHOLESTEROL  PATHOPHYSIOLOGY  MAINTENANCE  HOMEOSTASIS  METABOLISM  PHYSIOLOGY  
SINGLE-CELL TRANSCRIPTOMIC ATLAS OF PRIMATE CARDIOPULMONARY AGING 期刊论文
Cell ReseaRch, 2021, 卷号: 31, 期号: 4, 页码: 415-432
作者:  Ma Shuai;  Sun Shuhui;  Li Jiaming;  Fan Yanling;  Qu Jing;  Sun Liang;  Wang Si;  Zhang Yiyuan;  Yang Shanshan;  Liu Zunpeng;  Wu Zeming;  Zhang Sheng;  Wang Qiaoran;  Zheng Aihua;  Duo Shuguang;  Yu Yang;  Belmonte Juan Carlos Izpisua;  Chan Piu;  Zhou Qi;  Song Moshi;  Zhang Weiqi;  Liu Guang-Hui
浏览  |  Adobe PDF(6850Kb)  |  收藏  |  浏览/下载：1854/286  |  提交时间：2023/04/17
Single-cell transcriptomic atlas of primate cardiopulmonary aging 期刊论文
CELL RESEARCH, 2021, 卷号: 31, 期号: 4, 页码: 415-432
作者:  Ma S(马帅);  Sun Shuhui;  Li Jiaming;  Fan Yanling;  Qu J(曲静);  Sun Liang;  Wang S(王思);  Zhang Yiyuan;  Yang Shanshan;  Liu Zunpeng;  Wu Zeming;  Zhang Sheng;  Wang Qiaoran;  Zheng AH(郑爱华);  Duo Shuguang;  Yu Yang;  Belmonte Juan Carlos Izpisua;  Chan Piu;  Zhou Q(周琪);  Song MS(宋默识);  Zhang Weiqi;  Liu GH(刘光慧)
浏览  |  Adobe PDF(6850Kb)  |  收藏  |  浏览/下载：942/179  |  提交时间：2021/10/26
SINGLE-CELL TRANSCRIPTOMIC ATLAS OF PRIMATE CARDIOPULMONARY AGING 期刊论文
Cell ReseaRch, 2021, 卷号: 31, 期号: 4, 页码: 415-432
作者:  Ma Shuai;  Sun Shuhui;  Li Jiaming;  Fan Yanling;  Qu Jing;  Sun Liang;  Wang Si;  Zhang Yiyuan;  Yang Shanshan;  Liu Zunpeng;  Wu Zeming;  Zhang Sheng;  Wang Qiaoran;  Zheng Aihua;  Duo Shuguang;  Yu Yang;  Belmonte Juan Carlos Izpisua;  Chan Piu;  Zhou Qi;  Song Moshi;  Zhang Weiqi;  Liu Guang-Hui
浏览  |  Adobe PDF(6850Kb)  |  收藏  |  浏览/下载：874/237  |  提交时间：2023/04/17